Voinova

Classification of digital microscopy systems and elements of the automated microscopy complexes with an external automation set are considered. A new method and variants of corresponding device for automation of microscope stage, suggesting, in contrast to existing analogs, the use of own microscope stage without its disassembling is proposed. The stated solution can significantly reduce the cost of microscope automation set and make it available for wide practical application.

The paper presents results of developing an automated complex for determination of the hormonal status of breast cancer using an immunocytochemistry method. The complex performs automated scanning of medication and image capturing by means of an automated computer-driven microscope, as well as automated image analysis which results in estimation of Allred’s scores; the developed complex is capable of visual verification and correction of analysis results if it is necessary. Experimental studies demonstrated high repeatable accuracy of automated analysis results and agreement of automatically drawn conclusions on the hormonal status of breast cancer with the ones obtained by cytologist during visual microscopic examination.